Share Email Print
cover

Proceedings Paper

THz spectroscopy based high sensitivity measurement of protein using a metal mesh device
Author(s): T. Suzuki; Y. Ogawa; T. Kondo; S. Kamba; N. Kondo
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

A label-free bioaffinity sensor working in terahertz (THz) region with a nitrocellulose membrane filter was demonstrated, which is based on the resonant transmission phenomenon and the dip in the spectra of the metal mesh device. By using this sensor, we succeeded in the highly sensitive detection of small amounts of protein avidin-biotin complex. A distinct change of transmittance caused by shift of the transmission dip was observed for 8 ng/mm2 (74 fmol) of horseradish peroxidase (HRP) labeled avidin. The sensing method has broad utility for many reactions on the membrane filter as a simple and rapid sensor.

Paper Details

Date Published: 2 June 2011
PDF: 6 pages
Proc. SPIE 8027, Sensing for Agriculture and Food Quality and Safety III, 802706 (2 June 2011); doi: 10.1117/12.886691
Show Author Affiliations
T. Suzuki, Kyoto Univ. Graduate School of Agriculture (Japan)
Y. Ogawa, Kyoto Univ. Graduate School of Agriculture (Japan)
T. Kondo, Murata Manufacturing Co., Ltd. (Japan)
S. Kamba, Murata Manufacturing Co., Ltd. (Japan)
N. Kondo, Kyoto Univ. Graduate School of Agriculture (Japan)


Published in SPIE Proceedings Vol. 8027:
Sensing for Agriculture and Food Quality and Safety III
Moon S. Kim; Shu-I Tu; Kaunglin Chao, Editor(s)

© SPIE. Terms of Use
Back to Top