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Proceedings Paper

Field-based multiplex and quantitative assay platforms for diagnostics
Author(s): Srivatsa Venkatasubbarao; C. Edward Dixon; Russell Chipman; Axel Scherer; Manal Beshay; Lothar U. Kempen; Jai Ganesh Chandra Sekhar; Hong Yan; Ava Puccio; David Okonkwo; Stephen McClain; Noah Gilbert; Saurabh Vyawahare
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Paper Abstract

The U.S. military has a continued interest in the development of handheld, field-usable sensors and test kits for a variety of diagnostic applications, such as traumatic brain injury (TBI) and infectious diseases. Field-use presents unique challenges for biosensor design, both for the readout unit and for the biological assay platform. We have developed robust biosensor devices that offer ultra-high sensitivity and also meet field-use needs. The systems under development include a multiplexed quantitative lateral flow test strip for TBI diagnostics, a field test kit for the diagnosis of pathogens endemic to the Middle East, and a microfluidic assay platform with a label-free reader for performing complex biological automated assays in the field.

Paper Details

Date Published: 17 May 2011
PDF: 11 pages
Proc. SPIE 8029, Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring; and Biometric Technology for Human Identification VIII, 80290P (17 May 2011); doi: 10.1117/12.886661
Show Author Affiliations
Srivatsa Venkatasubbarao, Intelligent Optical Systems, Inc. (United States)
C. Edward Dixon, Univ. of Pittsburgh (United States)
Russell Chipman, The Univ. of Arizona (United States)
Axel Scherer, California Institute of Technology (United States)
Manal Beshay, Intelligent Optical Systems, Inc. (United States)
Lothar U. Kempen, Intelligent Optical Systems, Inc. (United States)
Jai Ganesh Chandra Sekhar, Intelligent Optical Systems, Inc. (United States)
Hong Yan, Univ. of Pittsburgh (United States)
Ava Puccio, Univ. of Pittsburgh (United States)
David Okonkwo, Univ. of Pittsburgh (United States)
Stephen McClain, The Univ. of Arizona (United States)
Noah Gilbert, The Univ. of Arizona (United States)
Saurabh Vyawahare, California Institute of Technology (United States)


Published in SPIE Proceedings Vol. 8029:
Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring; and Biometric Technology for Human Identification VIII
B. V. K. Vijaya Kumar; Sárka O. Southern; Kevin N. Montgomery; Salil Prabhakar; Arun A. Ross; Carl W. Taylor; Bernhard H. Weigl, Editor(s)

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