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Proceedings Paper

Surface scattering plasmon resonance fibre sensors: demonstration of rapid influenza A virus detection
Author(s): A. Franςois; J. Boehm; S. Y, Oh; T. Kok; T. M. Monro
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Paper Abstract

The management of threats such as pandemics and explosives, and of health and the environment requires the rapid deployment of highly sensitive detection tools. Sensors based on Surface Plasmon Resonance (SPR) allow rapid, labelfree, highly sensitive detection, and indeed this phenomenon underpins the only label-free optical biosensing technology that is available commercially. In these sensors, the existence of surface plasmons is inferred indirectly from absorption features that correspond to the coupling of light to the surface plasmon. Although SPR is not intrinsically a radiative process, under certain conditions the surface plasmon can itself couple to the local photon states, and emit light as first described byKretschmann. Here we show that by collecting and characterising this re-emitted light, it is possible to realise new SPR sensing architectures that are more compact, versatile and robust than existing approaches. This approach addresses existing practical limitations associated with current SPR technologies, including bulk, cost and calibration. It is applicable to a range of SPR geometries, including optical fibres, planar waveguides and prism configurations, and is in principle capable of detecting multiple analytes simultaneously. Moreover, this technique allows to combine SPR sensing and fluorescence sensing into a single platform which has never been demonstrated before and consequently use these two methods for a more reliable diagnostic. As an example, this approach has been used to demonstrate the rapid detection of the seasonal influenza virus.

Paper Details

Date Published: 2 June 2011
PDF: 11 pages
Proc. SPIE 8028, Fiber Optic Sensors and Applications VIII, 80280J (2 June 2011); doi: 10.1117/12.883825
Show Author Affiliations
A. Franςois, The Univ. of Adelaide (Australia)
J. Boehm, The Univ. of Adelaide (Australia)
S. Y, Oh, Institute of Medical and Veterinary Science (Australia)
T. Kok, Institute of Medical and Veterinary Science (Australia)
T. M. Monro, The Univ. of Adelaide (Australia)

Published in SPIE Proceedings Vol. 8028:
Fiber Optic Sensors and Applications VIII
Stephen J. Mihailov; Henry H. Du; Gary Pickrell, Editor(s)

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