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Proceedings Paper

Temperature elevations in prostatic tumors during laser photothermal therapy
Author(s): L. Zhu; A. Attaluri; H. Cai; R. Edziah; E. Lalanne; C. Bieberich; R. Ma; A. M. Johnson
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Paper Abstract

In vivo experiments were performed to measure temperature elevations in prostatic tumors implanted in mice during laser photothermal therapy using nanorods. Ti:Sapphire laser tuned at 800 nm irradiating the surface of the tumor delivered an average laser power of 0.5 - 1.0 W, equivalent to a laser radiance of 1.3-2.6 W/cm2. The temperature elevations measured by two thermocouples located at the center and bottom of the tumor have shown non-uniform tumor temperature field, 10-30°C above the baseline temperature of 37°C. The experimental studies have demonstrated the capability of confining laser energy in tumors by a very small amount of nanorod solution.

Paper Details

Date Published: 26 May 2011
PDF: 4 pages
Proc. SPIE 8025, Smart Biomedical and Physiological Sensor Technology VIII, 80250G (26 May 2011); doi: 10.1117/12.882746
Show Author Affiliations
L. Zhu, Univ. of Maryland, Baltimore County (United States)
A. Attaluri, Univ. of Maryland, Baltimore County (United States)
H. Cai, Univ. of Maryland, Baltimore County (United States)
R. Edziah, Univ. of Maryland, Baltimore County (United States)
E. Lalanne, Univ. of Maryland, Baltimore County (United States)
C. Bieberich, Univ. of Maryland, Baltimore County (United States)
R. Ma, Univ. of Maryland, Baltimore County (United States)
A. M. Johnson, Univ. of Maryland, Baltimore County (United States)


Published in SPIE Proceedings Vol. 8025:
Smart Biomedical and Physiological Sensor Technology VIII
Brian M. Cullum; Eric S. McLamore, Editor(s)

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