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Proceedings Paper

Nano-engineered materials based on fullerenes: synthesis and biomedical applications
Author(s): Radu Claudiu Fierascu; Irina Dumitriu; Rodica Mariana Ion; Monica Neagu; Carolina Constantin; Crina Stavaru
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Paper Abstract

The nanoengineering of various materials for biomedical application has became in the last decade one of the most important research areas, due to the continuous struggle to find new and more efficient instruments for the therapy of cancer and other diseases. Attempts to obtain functionalized derivatives of fullerene seek the synthesis of watersoluble materials, in order to investigate their effects in physiological conditions. International studies on the biological properties of fullerenes and their derivatives, are now targeted towards anti-tumor effects, pharmacology and their involvement in oxidative stress. Their toxicity, demonstrated both in vitro and in vivo is important for characterization and selection of applications. Phototoxicity of some molecules of fullerenes has been identified as future therapeutic tool. The present paper describes the synthesis, characterization and some biomedical applications of some nanomaterials based on fullerenes.

Paper Details

Date Published: 8 December 2010
PDF: 7 pages
Proc. SPIE 7821, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies V, 78211J (8 December 2010); doi: 10.1117/12.882045
Show Author Affiliations
Radu Claudiu Fierascu, ICECHIM (Romania)
Valahia Univ. of Targoviste (Romania)
Irina Dumitriu, ICECHIM (Romania)
Valahia Univ. of Targoviste (Romania)
Rodica Mariana Ion, ICECHIM (Romania)
Valahia Univ. of Targoviste (Romania)
Monica Neagu, Victor Babes National Institute for Pathology and Biomedical Sciences (Romania)
Carolina Constantin, Victor Babes National Institute for Pathology and Biomedical Sciences (Romania)
Crina Stavaru, INCDMI Cantacuzino (Romania)


Published in SPIE Proceedings Vol. 7821:
Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies V

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