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Proceedings Paper

System-independent assessment of OCT axial resolution with a "bar chart" phantom
Author(s): Anant Agrawal; Robert Chang; Megan Connors; Christopher Stafford; Jeeseong Hwang; Joshua Pfefer
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Paper Abstract

We present a optical phantom approach for the characterization of OCT axial resolution and contrast via multilayered "bar charts." We explored two methods to fabricate these phantoms: the first is based on monolayers of light-scattering microspheres with an intervening layer of transparent silicone, and the second involves alternating layers of scatteringenhanced silicone and transparent silicone. Varying the diameter of the microspheres and the thickness of the silicone layers permits different spatial frequencies to be realized in the axial dimension of the phantoms. Because the phantom's dimensions are accurately known independent of the OCT system, no information about the system's spatial calibration is required. We quantified the degree to which the bars in each phantom could be resolved with OCT, which provides insights into the axial contrast transfer function. Initial testing of these phantoms on time-resolved and Fourier-domain OCT platforms indicated that our approach can provide accurate, system-independent estimates of resolution.

Paper Details

Date Published: 11 February 2011
PDF: 7 pages
Proc. SPIE 7906, Optical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III, 79060R (11 February 2011); doi: 10.1117/12.880958
Show Author Affiliations
Anant Agrawal, U.S. Food and Drug Administration (United States)
Robert Chang, National Institute of Standards and Technology (United States)
Megan Connors, U.S. Food and Drug Administration (United States)
Christopher Stafford, National Institute of Standards and Technology (United States)
Jeeseong Hwang, National Institute of Standards and Technology (United States)
Joshua Pfefer, U.S. Food and Drug Administration (United States)


Published in SPIE Proceedings Vol. 7906:
Optical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III
Gerard L. Coté; Robert J. Nordstrom, Editor(s)

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