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Proceedings Paper

Silicon photonic microring resonator arrays for scalable and multiplexable bioanalysis
Author(s): Matthew S. Luchansky; Adam L. Washburn; Abraham J. Qavi; Jared T. Kindt; Melinda S. McClellan; Ryan C. Bailey
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Paper Abstract

Silicon photonic devices, such as SOI microring resonators, have optical properties that are incredibly responsive to changes in the local dielectric environment accompanying a biological binding event at or near the ring surface. We have developed a platform in which arrays of uniquely addressable microrings are functionalized with target-specific capture agents so as to create a powerful tool for multiplexed biomolecular detection. We will discuss applications of this technology to the multiplexed detection of DNA, RNA, and proteins in clinically-relevant matrices, and will also describe the rigorous empirical determination of key sensitivity metrics.

Paper Details

Date Published: 8 February 2011
PDF: 4 pages
Proc. SPIE 7888, Frontiers in Biological Detection: From Nanosensors to Systems III, 788802 (8 February 2011); doi: 10.1117/12.880492
Show Author Affiliations
Matthew S. Luchansky, Univ. of Illinois at Urbana-Champaign (United States)
Adam L. Washburn, Univ. of Illinois at Urbana-Champaign (United States)
Abraham J. Qavi, Univ. of Illinois at Urbana-Champaign (United States)
Jared T. Kindt, Univ. of Illinois at Urbana-Champaign (United States)
Melinda S. McClellan, Univ. of Illinois at Urbana-Champaign (United States)
Ryan C. Bailey, Univ. of Illinois at Urbana-Champaign (United States)


Published in SPIE Proceedings Vol. 7888:
Frontiers in Biological Detection: From Nanosensors to Systems III
Benjamin L. Miller; Philippe M. Fauchet, Editor(s)

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