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Proceedings Paper

Development of an absorption-based tomographic system for mapping the human microvasculature
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Paper Abstract

There exist numerous planar imaging methods for mapping the human microvasculature. In medical diagnostics, tomography is preferred over surface imaging for the simple reason that biological organs are 3-dimensional in nature. The aim of this work is to create a novel technique to non-invasively map the concentration of red blood cells in the human microcirculation allowing 3-dimensional image reconstruction. We propose a tomographic system which is based on absorption contrast imaging. A Michelson interferometry method is employed using a broadband, white light source. This work details preliminary results of the calibration procedure of a 'bulk' system. A mirror, reflectance standards, glass-mirror arrangement, and color filter arrangement were used as samples. The resultant interference patterns from each were imaged and analyzed.

Paper Details

Date Published: 10 February 2011
PDF: 8 pages
Proc. SPIE 7898, Dynamics and Fluctuations in Biomedical Photonics VIII, 78980N (10 February 2011); doi: 10.1117/12.880047
Show Author Affiliations
Paul M. McNamara, Univ. of Limerick (Ireland)
Royal College of Surgeons (Ireland)
Enock Jonathan, Univ. of Limerick (Ireland)
Royal College of Surgeons (Ireland)
Martin J. Leahy, Univ. of Limerick (Ireland)
Royal College of Surgeons (Ireland)

Published in SPIE Proceedings Vol. 7898:
Dynamics and Fluctuations in Biomedical Photonics VIII
Valery V. Tuchin; Donald D. Duncan; Kirill V. Larin; Martin J. Leahy; Ruikang K. Wang, Editor(s)

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