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Proceedings Paper

Multimodal diagnostic approach for functional imaging of tumor vascular network and blood microcirculation
Author(s): Vyacheslav Kalchenko; Noa Madar-Balakirski; Yuri Kuznetsov; Igor Meglinski; Alon Harmelin
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Paper Abstract

We present a multi-modal optical diagnostic approach utilizing a combined use of Fluorescence Intravital Microscopy and Dynamic Light Scattering for in vivo functional imaging of tumor vascular network and blood microcirculation. Fluorescence Intravital Microscopy is used for imaging of tumor and tumor surroundings, whereas Dynamic Light Scattering is applied for imaging of vascular network and blood microcirculation. The obtained results demonstrate that presented multi-modal imaging approach has a great potential in vascular biology and can significantly expand the capabilities of tumor angiogenesis studies and notably contribute to the development of cancer treatment.

Paper Details

Date Published: 11 February 2011
PDF: 7 pages
Proc. SPIE 7898, Dynamics and Fluctuations in Biomedical Photonics VIII, 78980L (11 February 2011); doi: 10.1117/12.879523
Show Author Affiliations
Vyacheslav Kalchenko, Weizmann Institute of Science (Israel)
Noa Madar-Balakirski, Weizmann Institute of Science (Israel)
Yuri Kuznetsov, Weizmann Institute of Science (Israel)
Igor Meglinski, Univ. of Otago (New Zealand)
Alon Harmelin, Weizmann Institute of Science (Israel)


Published in SPIE Proceedings Vol. 7898:
Dynamics and Fluctuations in Biomedical Photonics VIII
Valery V. Tuchin; Donald D. Duncan; Kirill V. Larin; Martin J. Leahy; Ruikang K. Wang, Editor(s)

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