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Proceedings Paper

In vitro assessment of fiber sweeping angle during Q-switched 532-nm laser tissue ablation
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Paper Abstract

Photoselective vaporization of the prostate (PVP) has been widely used to treat benign prostatic hyperplasia (BPH). It is well regarded as a safe and minimally invasive procedure and an alternative to the gold standard transurethral resection of the prostate (TURP). Despite of its greatness, as well aware of, the operative procedure time during the PVP is still prolonged. Such attempts have been tried out in order to shorten the operative time and increase its efficacy. However, scientific study to investigate techniques used during the PVP is still lacking. The objective of this study is to investigate how sweeping angle might affect the PVP performance. Porcine kidneys acquired from a local grocery store were used (N=140). A Q-switched 532-nm GreenLight XPSTM (American Medical Systems, Inc., MN, USA), together with 750- μm core MoXyTM fiber, was set to have power levels of 120 W and 180 W. Treatment speed and sweeping speed were fixed at 2 mm/s and 0.5 sweep/s, respectively. Sweeping angles were varied from 0 (no sweeping motion) to 120 degree. Ablation rate, depth, and coagulation zone were measured and quantified. Tissue ablation rate was peaked at 15 and 30 degree for both 120- and 180-W power levels and dramatically decreased beyond 60 degree. At 180 W, ablation rate increased 20% at 30 degree compared to 0 degree. This study demonstrated that ablation rate could be maximized and was contingent upon sweeping angle.

Paper Details

Date Published: 17 February 2011
PDF: 5 pages
Proc. SPIE 7883, Photonic Therapeutics and Diagnostics VII, 78831J (17 February 2011); doi: 10.1117/12.879271
Show Author Affiliations
Danop Rajabhandharaks, American Medical Systems (United States)
Hyun Wook Kang, American Medical Systems (United States)
Woo Jin Ko, Columbia Univ. Medical Ctr. (United States)
Douglas Stinson, American Medical Systems (United States)
Benjamin Choi, Weill Cornell Univ. Medical Ctr. (United States)

Published in SPIE Proceedings Vol. 7883:
Photonic Therapeutics and Diagnostics VII
Kenton W. Gregory M.D.; Nikiforos Kollias; Andreas Mandelis; Henry Hirschberg M.D.; Hyun Wook Kang; Anita Mahadevan-Jansen; Brian Jet-Fei Wong M.D.; Justus F. R. Ilgner M.D.; Bodo E. Knudsen M.D.; E. Duco Jansen; Steen J. Madsen; Guillermo J. Tearney; Bernard Choi; Haishan Zeng; Laura Marcu, Editor(s)

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