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Proceedings Paper

Tumor characterization by chromophore concentrations in small animals using a hybrid MRI-DOT system
Author(s): Mitchell Hsing; Yuting Lin; Mehmet Burcin Unlu; Orhan Nalcioglu; Gultekin Gulsen
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Paper Abstract

In vivo experiments using a hybrid DOT and MRI system are undertaken on small animals in this study. MRI structural a priori information is utilized for constraining and guiding DOT chromophore reconstruction. Even though in the past, multi-wavelength DOT has been extensively evaluated with phantom and clinical studies, there have been very few small animal studies reported in literature. In this small animal study, chromophore reconstruction results for different tumor types are presented and compared. The goal of this study is to evaluate the performance of the hybrid MRI-DOT system in vivo.

Paper Details

Date Published: 10 February 2011
PDF: 5 pages
Proc. SPIE 7892, Multimodal Biomedical Imaging VI, 78920L (10 February 2011); doi: 10.1117/12.879029
Show Author Affiliations
Mitchell Hsing, Univ. of California, Irvine (United States)
Yuting Lin, Univ. of California, Irvine (United States)
Mehmet Burcin Unlu, Bogazici Univ. (Turkey)
Orhan Nalcioglu, Univ. of California, Irvine (United States)
Gultekin Gulsen, Univ. of California, Irvine (United States)

Published in SPIE Proceedings Vol. 7892:
Multimodal Biomedical Imaging VI
Fred S. Azar; Xavier Intes, Editor(s)

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