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Proceedings Paper

Breast imaging with ultrasound tomography: update on a comparative study with MR
Author(s): Bryan Ranger; Peter Littrup; Neb Duric; Cuiping Li; Steven Schmidt; Olsi Rama; Lisa Bey-Knight
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Paper Abstract

The objective of this study is to present imaging parameters and display thresholds of an ultrasound tomography (UST) prototype in order to demonstrate analogous visualization of overall breast anatomy and lesions relative to magnetic resonance (MR). Thirty-six women were imaged with MR and our UST prototype. The UST scan generated sound speed, attenuation, and reflection images and were subjected to variable thresholds then fused together into a single UST image. Qualitative and quantitative comparisons of MR and UST images were utilized to identify anatomical similarities and mass characteristics. Overall, UST demonstrated the ability to visualize and characterize breast tissues in a manner comparable to MR without the use of IV contrast. For optimal visualization, fused images utilized thresholds of 1.46±0.1 km/s for sound speed to represent architectural features of the breast including parenchyma. An arithmetic combination of images using the logical .AND. and .OR. operators, along with thresholds of 1.52±0.03 km/s for sound speed and 0.16±0.04 dB/cm for attenuation, allowed for mass detection and characterization similar to MR.

Paper Details

Date Published: 26 March 2011
PDF: 6 pages
Proc. SPIE 7968, Medical Imaging 2011: Ultrasonic Imaging, Tomography, and Therapy, 79680M (26 March 2011); doi: 10.1117/12.878922
Show Author Affiliations
Bryan Ranger, Karmanos Cancer Institute, Wayne State Univ. (United States)
Peter Littrup, Karmanos Cancer Institute, Wayne State Univ. (United States)
Neb Duric, Karmanos Cancer Institute, Wayne State Univ. (United States)
Cuiping Li, Karmanos Cancer Institute, Wayne State Univ. (United States)
Steven Schmidt, Karmanos Cancer Institute, Wayne State Univ. (United States)
Olsi Rama, Karmanos Cancer Institute, Wayne State Univ. (United States)
Lisa Bey-Knight, Karmanos Cancer Institute, Wayne State Univ. (United States)


Published in SPIE Proceedings Vol. 7968:
Medical Imaging 2011: Ultrasonic Imaging, Tomography, and Therapy
Jan D'hooge; Marvin M. Doyley, Editor(s)

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