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Proceedings Paper

Target detection and characterization using a hybrid handheld diffuse optical tomography and photoacoustic tomography system
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Paper Abstract

A handheld photoacoustic tomography-guided diffuse optical tomography system for imaging deeply-seated targets in scattering media is presented. This hybrid imager consists of a probe with an ultrasound transducer in the center and straddled by two optical fibers for taking photoacoustic images. The diffuse optical tomography component comprises of 9 light-source fibers for delivering light to the imaged tissue, and 14 detector fibers for collecting the light. Single- and two-phantom targets of high and low optical contrasts were immersed in a scattering intralipid solution to depths of up to 3cm and imaged. The reconstructed absorption coefficients of the targets with guidance from photoacoustic tomography were compared to those obtained with a-priori depth-only information, and no a-priori information. The reconstructed absorption maps yielded as much as 2.6-fold improvement in the quantification accuracy compared to the cases with no guidance from photoacoustic tomography.

Paper Details

Date Published: 1 March 2011
PDF: 9 pages
Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 789614 (1 March 2011); doi: 10.1117/12.878913
Show Author Affiliations
Patrick D. Kumavor, Univ. of Connecticut (United States)
Andres Aguirre, Univ. of Connecticut (United States)
Chen Xu, Univ. of Connecticut (United States)
John Gamelin, Univ. of Connecticut (United States)
Yasaman Ardeshirpour, Univ. of Connecticut (United States)
Behnoosh Tavakoli, Univ. of Connecticut (United States)
Saeid Zanganeh, Univ. of Connecticut (United States)
Umar S. Alqasemi, Univ. of Connecticut (United States)
Quing Zhu, Univ. of Connecticut (United States)

Published in SPIE Proceedings Vol. 7896:
Optical Tomography and Spectroscopy of Tissue IX
Bruce Jason Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

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