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Proceedings Paper

A pneumatic actuated microfluidic beads-trapping device
Author(s): Guocheng Shao; Ziliang Cai; Jun Wang; Wanjun Wang; Yuehe Lin
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Paper Abstract

The development of a polydimethylsiloxane (PDMS) microfluidic microbeads trapping device is reported in this paper. Besides fluid channels, the proposed device includes a pneumatic control chamber and a beads-trapping chamber with a filter array structure. The pneumatic flow control chamber and the beads-trapping chamber are vertically stacked and separated by a thin membrane. By adjusting the pressure in the pneumatic control chamber, the membrane can either be pushed against the filter array to set the device in "trapping mode" or be released to set the device in "releasing mode". In this paper, a computational fluid dynamics simulation was conducted to optimize the geometry design of the filter array structure; the device fabrication was also carried out. The prototype device was tested and the preliminary experimental results showed that it can be used as a beads-trapping unit for various biochemistry and analytical chemistry applications, especially for flow injection analysis systems.

Paper Details

Date Published: 14 February 2011
PDF: 5 pages
Proc. SPIE 7929, Microfluidics, BioMEMS, and Medical Microsystems IX, 792908 (14 February 2011); doi: 10.1117/12.878468
Show Author Affiliations
Guocheng Shao, Louisiana State Univ. (United States)
Ziliang Cai, Louisiana State Univ. (United States)
Jun Wang, Pacific Northwest National Lab. (United States)
Wanjun Wang, Louisiana State Univ. (United States)
Yuehe Lin, Pacific Northwest National Lab. (United States)

Published in SPIE Proceedings Vol. 7929:
Microfluidics, BioMEMS, and Medical Microsystems IX
Holger Becker; Bonnie L. Gray, Editor(s)

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