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Proceedings Paper

A new technology for terahertz imaging in breast cancer margin determination
Author(s): Sigfrid Yngvesson; Benjamin St. Peter; Paul Siqueira; Patrick Kelly; Stephen Glick; Andrew Karellas
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Paper Abstract

In this paper we describe a project for designing, developing and translating a THz imaging device for monitoring margins from extracted tissue during surgical breast cancer conservation procedures. In this application, the reflective and transmission properties of extracted tissue are monitored, in near real-time using a fine-beam THz signal which is sensitive to the presence of liquid and bound water content. In this way, it is intended that the extracted tissue will be studied in the operating theatre to determine during surgery, whether or not the region of malignant tissue has been fully excised from the patient. In the early stages of this project, we are determining to what degree an existing THz system at the University of Massachusetts (UMass) in Amherst is able to differentiate between breast carcinoma, normal fibroglandular and adipose tissues. This is achieved through close collaboration with a surgical and radiological team at the UMass-Worcester medical school and involves post-surgical recovered tissues. As part of this work, we are describing the system, measurement methodology, and first results that were obtained to calibrate the imaging system.

Paper Details

Date Published: 16 March 2011
PDF: 8 pages
Proc. SPIE 7961, Medical Imaging 2011: Physics of Medical Imaging, 796150 (16 March 2011); doi: 10.1117/12.878337
Show Author Affiliations
Sigfrid Yngvesson, Univ. of Massachusetts Amherst (United States)
Benjamin St. Peter, Univ. of Massachusetts Amherst (United States)
Paul Siqueira, Univ. of Massachusetts Amherst (United States)
Patrick Kelly, Univ. of Massachusetts Amherst (United States)
Stephen Glick, Univ. of Massachusetts Medical School (United States)
Andrew Karellas, Univ. of Massachusetts Medical School (United States)

Published in SPIE Proceedings Vol. 7961:
Medical Imaging 2011: Physics of Medical Imaging
Norbert J. Pelc; Ehsan Samei; Robert M. Nishikawa, Editor(s)

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