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Proceedings Paper

High-order noise analysis for low dose iterative image reconstruction methods: ASIR, IRIS, and MBAI
Author(s): Synho Do; Sarabjeet Singh; Mannudeep K. Kalra; W. Clem Karl; Thomas J. Brady; Homer Pien
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Paper Abstract

Iterative reconstruction techniques (IRTs) has been shown to suppress noise significantly in low dose CT imaging. However, medical doctors hesitate to accept this new technology because visual impression of IRT images are different from full-dose filtered back-projection (FBP) images. Most common noise measurements such as the mean and standard deviation of homogeneous region in the image that do not provide sufficient characterization of noise statistics when probability density function becomes non-Gaussian. In this study, we measure L-moments of intensity values of images acquired at 10% of normal dose and reconstructed by IRT methods of two state-of-art clinical scanners (i.e., GE HDCT and Siemens DSCT flash) by keeping dosage level identical to each other. The high- and low-dose scans (i.e., 10% of high dose) were acquired from each scanner and L-moments of noise patches were calculated for the comparison.

Paper Details

Date Published: 15 March 2011
PDF: 6 pages
Proc. SPIE 7961, Medical Imaging 2011: Physics of Medical Imaging, 79610I (15 March 2011); doi: 10.1117/12.878222
Show Author Affiliations
Synho Do, Massachusetts General Hospital (United States)
Harvard Medical School (United States)
Sarabjeet Singh, Massachusetts General Hospital (United States)
Harvard Medical School (United States)
Mannudeep K. Kalra, Massachusetts General Hospital (United States)
Harvard Medical School (United States)
W. Clem Karl, Boston Univ. (United States)
Thomas J. Brady, Massachusetts General Hospital (United States)
Harvard Medical School (United States)
Homer Pien, Massachusetts General Hospital (United States)
Harvard Medical School (United States)


Published in SPIE Proceedings Vol. 7961:
Medical Imaging 2011: Physics of Medical Imaging
Norbert J. Pelc; Ehsan Samei; Robert M. Nishikawa, Editor(s)

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