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Proceedings Paper

Mouse whole-body organ mapping by non-rigid registration approach
Author(s): Di Xiao; David Zahra; Pierrick Bourgeat; Paula Berghofer; Oscar Acosta Tamayo; Heather Green; Marie Claude Gregoire; Olivier Salvado
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Paper Abstract

Automatic small animal whole-body organ registration is challenging because of subject's joint structure, posture and position difference and loss of reference features. In this paper, an improved 3D shape context based non-rigid registration method is applied for mouse whole-body skeleton registration and lung registration. A geodesic path based non-rigid registration method is proposed for mouse torso skin registration. Based on the above registration methods, a novel non-rigid registration framework is proposed for mouse whole-body organ mapping from an atlas to new scanned CT data. A preliminary experiment was performed to test the method on lung and skin registration. A whole-body organ mapping was performed on three target data and the selected organs were compared with the manual outlining results. The robust of the method has been demonstrated.

Paper Details

Date Published: 9 March 2011
PDF: 7 pages
Proc. SPIE 7965, Medical Imaging 2011: Biomedical Applications in Molecular, Structural, and Functional Imaging, 79650E (9 March 2011); doi: 10.1117/12.877921
Show Author Affiliations
Di Xiao, Commonwealth Scientific and Industrial Research Organisation (Australia)
David Zahra, Australian Nuclear Science and Technology Organisation (Australia)
Pierrick Bourgeat, Commonwealth Scientific and Industrial Research Organisation (Australia)
Paula Berghofer, Australian Nuclear Science and Technology Organisation (Australia)
Oscar Acosta Tamayo, Commonwealth Scientific and Industrial Research Organisation (Australia)
Univ. de Rennes 1 (France)
Heather Green, Australian Nuclear Science and Technology Organisation (Australia)
Marie Claude Gregoire, Australian Nuclear Science and Technology Organisation (Australia)
Olivier Salvado, Commonwealth Scientific and Industrial Research Organisation (Australia)


Published in SPIE Proceedings Vol. 7965:
Medical Imaging 2011: Biomedical Applications in Molecular, Structural, and Functional Imaging
John B. Weaver; Robert C. Molthen, Editor(s)

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