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Proceedings Paper

Multifunctional hybrid nanoparticles for two-photon fluorescence imaging and photodynamic therapy
Author(s): Patrice L. Baldeck; Mathieu Maurin; Cecile Philipot; Soraya Zaiba; Thibault Gallavardin; Olivier Maury; Chantal Andraud; Fabien Dubois; Alain Ibanez; Frédéric Lerouge; Stéphane Parola; Olivier Stephan; Baudwin van Der Sanden
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Paper Abstract

We review our work on several strategies to elaborate multifunctional nanoparticules for two-photon imaging or/and photodynamic therapy. Our first strategy is based on the incorporation of two-photon hydrophobic fluorophors in bio-compatible pluronic micelles using the mini-emulsion technique. Our second strategy is based on fluorescent organic nanocrystal grown in silicate spheres. These core-shell hybrid nanoparticles are obtained by a spray-drying process from sol-gel solutions. Our third strategy consists in the encapsulation of hydrophilic molecules in the water core of gold nanospheres. They are obtained by a stabilized emulsion in biphasic liquid-liquid medium without surfactant.

Paper Details

Date Published: 21 February 2011
PDF: 7 pages
Proc. SPIE 7935, Organic Photonic Materials and Devices XIII, 79350S (21 February 2011); doi: 10.1117/12.877759
Show Author Affiliations
Patrice L. Baldeck, Lab. Interdisciplinaire de Physique, CNRS, Univ. Joseph Fourier (France)
Lab. de Chimie, CNRS, Univ. de Lyon 1 (France)
Mathieu Maurin, Lab. Interdisciplinaire de Physique, CNRS, Univ. Joseph Fourier (France)
Cecile Philipot, Institut Néel, CNRS, Univ. Joseph Fourier (France)
Soraya Zaiba, Lab. Interdisciplinaire de Physique, CNRS, Univ. Joseph Fourier (France)
Univ. M'hamed Bouguera (Algeria)
Thibault Gallavardin, Lab. de Chimie, CNRS, Univ. de Lyon 1 (France)
Olivier Maury, Lab. de Chimie, CNRS, Univ. de Lyon 1 (France)
Chantal Andraud, Lab. de Chimie, CNRS, Univ. de Lyon 1 (France)
Fabien Dubois, Institut Néel, CNRS, Univ. Joseph Fourier (France)
Alain Ibanez, Institut Néel, CNRS, Univ. Joseph Fourier (France)
Frédéric Lerouge, Lab. de Chimie, CNRS, Univ. de Lyon 1 (France)
Stéphane Parola, Lab. de Chimie, CNRS, Univ. de Lyon 1 (France)
Olivier Stephan, Lab. Interdisciplinaire de Physique, CNRS, Univ. Joseph Fourier (France)
Baudwin van Der Sanden, INSERM (France)


Published in SPIE Proceedings Vol. 7935:
Organic Photonic Materials and Devices XIII
Robert L. Nelson; François Kajzar; Toshikuni Kaino; Yasuhiro Koike, Editor(s)

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