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Proceedings Paper

Advanced capabilities of the multimodal adaptive optics imager
Author(s): Daniel X. Hammer; R. Daniel Ferguson; Mircea Mujat; David P. Biss; Nicusor V. Iftimia; Ankit H. Patel; Emily Plumb; Melanie Campbell; Jennifer L. Norris; Alfredo Dubra; Toco Y. P. Chui; James D. Akula; Anne B. Fulton
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Paper Abstract

We recently developed several versions of a multimodal adaptive optics (AO) retinal imager, which includes highresolution scanning laser ophthalmoscopy (SLO) and Fourier domain optical coherence tomography (FDOCT) imaging channels as well as an auxiliary wide-field line scanning ophthalmoscope (LSO). Some versions have also been equipped with a fluorescence channel and a retinal tracker. We describe the performance of three key features of the multimodal AO system including: simultaneous SLO/OCT imaging, which allows SLO/OCT co-registration; a small animal imaging port, which adjusts the beam diameter at the pupil from 7.5 to 2.5 mm for use with small animals ubiquitous in biological research or for extended depth-of-focus imaging in humans; and slow scan Doppler flowmetry imaging using the wide field auxiliary LSO imaging channel. The systems are currently deployed in several ophthalmology clinics and research laboratories and several investigations have commenced on patients with a variety of retinal diseases and animals in vision research.

Paper Details

Date Published: 16 February 2011
PDF: 11 pages
Proc. SPIE 7885, Ophthalmic Technologies XXI, 78850A (16 February 2011); doi: 10.1117/12.876579
Show Author Affiliations
Daniel X. Hammer, Physical Sciences Inc. (United States)
R. Daniel Ferguson, Physical Sciences Inc. (United States)
Mircea Mujat, Physical Sciences Inc. (United States)
David P. Biss, Physical Sciences Inc. (United States)
Nicusor V. Iftimia, Physical Sciences Inc. (United States)
Ankit H. Patel, Physical Sciences Inc. (United States)
Emily Plumb, Physical Sciences Inc. (United States)
Melanie Campbell, Univ. of Waterloo (Canada)
Jennifer L. Norris, Univ. of Rochester (United States)
Alfredo Dubra, Univ. of Rochester (United States)
Toco Y. P. Chui, Children's Hospital Boston (United States)
Harvard Medical School (United States)
James D. Akula, Children's Hospital Boston (United States)
Harvard Medical School (United States)
Anne B. Fulton, Children's Hospital Boston (United States)
Harvard Medical School (United States)

Published in SPIE Proceedings Vol. 7885:
Ophthalmic Technologies XXI
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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