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Proceedings Paper

Smart velocity ranging quantifiable optical microangiography
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Paper Abstract

We introduce a new type of Optical Microangiography (OMAG) called Quantifiable Optical Microangiography (QOMAG) which is capable of performing quantitative flow imaging with smart velocity ranging. In order to extracting multi-range velocity, two three dimensional data sets need to be acquired at the same imaging area. One data set performs dense scanning in B-scan direction and Doppler analysis was done at the basis of subsequent A-scans, while the other data set performs dense scanning in C-scan direction and Doppler analysis was done at the basis of consecutive B-scan. Since the velocity ranging is determined by the time interval between consecutive measurements of the spectral fringes, longer time interval will give us higher sensitivity to slow velocity. By simultaneous acquiring data sets with different time intervals, we can perform smart velocity ranging quantification on blood flow characterized by different velocity values. The feasibility of QOMAG for variable blood flow imaging is demonstrated by in vivo studies executed on cerebral blood flow of mouse model. Multi-range detailed blood flow map within intracranial Dura mater and cortex of mouse brain can be given by QOMAG.

Paper Details

Date Published: 10 February 2011
PDF: 4 pages
Proc. SPIE 7898, Dynamics and Fluctuations in Biomedical Photonics VIII, 78980K (10 February 2011); doi: 10.1117/12.875712
Show Author Affiliations
Zhongwei Zhi, Univ. of Washington (United States)
Ruikang K. Wang, Univ. of Washington (United States)


Published in SPIE Proceedings Vol. 7898:
Dynamics and Fluctuations in Biomedical Photonics VIII
Valery V. Tuchin; Donald D. Duncan; Kirill V. Larin; Martin J. Leahy; Ruikang K. Wang, Editor(s)

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