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Proceedings Paper

Label-free 3D optical imaging of microcirculation within sentinel lymph node in vivo
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Paper Abstract

Sentinel lymph node (SLN) is the first lymph node to drain wastes originated from cancerous tissue. There is a need for an in vivo imaging method that can image the intact SLN in order to further our understanding of its normal as well as abnormal functions. We report the use of ultrahigh sensitive optical microangiography (UHS-OMAG) to image functional microvascular and lymphatic vessel networks that innervate the intact lymph node in mice in vivo. The promising results show a potential role of UHS-OMAG in the future understanding and diagnosis of the SLN involvement in cancer development.

Paper Details

Date Published: 11 February 2011
PDF: 4 pages
Proc. SPIE 7889, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV, 788910 (11 February 2011); doi: 10.1117/12.875682
Show Author Affiliations
Yeongri Jung, Univ. of Washington (United States)
Zhongwei Zhi, Univ. of Washington (United States)
Ruikang K. Wang, Univ. of Washington (United States)


Published in SPIE Proceedings Vol. 7889:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

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