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Proceedings Paper

Simultaneous imaging of light-evoked activities in retinal photoreceptors and inner neurons
Author(s): Xin-Cheng Yao; Yi-Chao Li; Christianne Strang; Franklin R. Amthor; Lei Liu; Yang-Guo Li; Qiuxiang Zhang; Kent Keyser
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Paper Abstract

Simultaneous imaging of different retinal neurons functioning together can benefit better understanding of visual signal processing mechanisms. In this paper we demonstrate that intrinsic optical signal (IOS) imaging allows simultaneous monitoring of stimulus-evoked responses propagating from the photoreceptors to inner retinal neurons. High resolution imaging revealed robust IOSs at the photoreceptor, inner plexiform and ganglion cell layers. While IOSs of the photoreceptor layer were mainly confined to the area directly stimulated by the visible light; IOSs of inner retinal layers spread from the stimulus site into relatively large areas.

Paper Details

Date Published: 18 February 2011
PDF: 5 pages
Proc. SPIE 7883, Photonic Therapeutics and Diagnostics VII, 78834U (18 February 2011); doi: 10.1117/12.875289
Show Author Affiliations
Xin-Cheng Yao, The Univ. of Alabama at Birmingham (United States)
Yi-Chao Li, The Univ. of Alabama at Birmingham (United States)
Christianne Strang, The Univ. of Alabama at Birmingham (United States)
Franklin R. Amthor, The Univ. of Alabama at Birmingham (United States)
Lei Liu, The Univ. of Alabama at Birmingham (United States)
Yang-Guo Li, The Univ. of Alabama at Birmingham (United States)
Qiuxiang Zhang, The Univ. of Alabama at Birmingham (United States)
Kent Keyser, The Univ. of Alabama at Birmingham (United States)


Published in SPIE Proceedings Vol. 7883:
Photonic Therapeutics and Diagnostics VII
Kenton W. Gregory; Nikiforos Kollias; Andreas Mandelis; Henry Hirschberg; Hyun Wook Kang; Anita Mahadevan-Jansen; Brian Jet-Fei Wong; Justus F. R. Ilgner; Bodo E. Knudsen; E. Duco Jansen; Steen J. Madsen; Guillermo J. Tearney; Bernard Choi; Haishan Zeng; Laura Marcu, Editor(s)

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