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Proceedings Paper

Realtime temperature determination during retinal photocoagulation on patients
Author(s): Ralf Brinkmann; Stefan Koinzer; Kerstin Schlott; Lars Ptaszynski; Marco Bever; Alex Baade; Yoko Miura; Reginald Birngruber; Johann Roider
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Paper Abstract

Retinal photocoagulation is a long time established treatment for a variety of retinal diseases, most commonly applied for diabetic macular edema and diabetic retinopathy. The damage extent of the induced thermal coagulations depend on the temperature increase and the time of irradiation. So far, the induced temperature rise is unknown due to intraocular variations in light transmission and scattering and RPE/choroidal pigmentation, which can vary inter- and intraindividually by more than a factor of four. Thus in clinical practice, often stronger and deeper coagulations are applied than therapeutically needed, which lead to extended retinal damage and strong pain perception. The final goal of this project focuses on a dosimetry control, which automatically generates a desired temperature profile and thus coagulation strength for every individual coagulation spot, ideally unburden the ophthalmologist from any laser settings. In this paper we present the first realtime temperature measurements achieved on patients during retinal photocoagulation by means of an optoacoustic method, making use of the temperature dependence of the thermal expansion coefficient of retinal tissue. Therefore, nanosecond probe laser pulses are repetitively and simultaneously applied with the treatment radiation in order to excite acoustic waves, which are detected at the cornea with an ultrasonic transducer embedded in the contact lens and then are processed by PC.

Paper Details

Date Published: 11 February 2011
PDF: 11 pages
Proc. SPIE 7885, Ophthalmic Technologies XXI, 78850R (11 February 2011); doi: 10.1117/12.875276
Show Author Affiliations
Ralf Brinkmann, Medizinisches Laserzentrum Lübeck GmbH (Germany)
Univ. zu Lübeck (Germany)
Stefan Koinzer, Eye Clinic Univ. of Schleswig-Holstein (Germany)
Kerstin Schlott, Medizinisches Laserzentrum Lübeck GmbH (Germany)
Univ. zu Lübeck (Germany)
Lars Ptaszynski, Medizinisches Laserzentrum Lübeck GmbH (Germany)
Marco Bever, Medizinisches Laserzentrum Lübeck GmbH (Germany)
Alex Baade, Medizinisches Laserzentrum Lübeck GmbH (Germany)
Yoko Miura, Univ. zu Lübeck (Germany)
Reginald Birngruber, Medizinisches Laserzentrum Lübeck GmbH (Germany)
Univ. zu Lübeck (Germany)
Johann Roider, Eye Clinic Univ. of Schleswig-Holstein (Germany)

Published in SPIE Proceedings Vol. 7885:
Ophthalmic Technologies XXI
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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