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Proceedings Paper

Cortical blood flow imaging of mouse stroke model by high-speed Spectral OCT
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Paper Abstract

We have developed and applied a high-speed Spectral OCT system to image small animal brains. OCT imaging with high spatial resolution and application of multi-parameter approach enabled cortical blood flow visualization. We imaged the brain vascular network of an anesthetized mouse stroke model. We demonstrated the impact of induced stroke on the brain vasculature. The preliminary studies have revealed local ischemia in the areas of the stroke.

Paper Details

Date Published: 23 March 2011
PDF: 7 pages
Proc. SPIE 7883, Photonic Therapeutics and Diagnostics VII, 788342 (23 March 2011); doi: 10.1117/12.875212
Show Author Affiliations
Ireneusz Grulkowski, Nicolaus Copernicus Univ. (Poland)
Grzegorz Wilczynski, Nencki Institute of Experimental Biology (Poland)
Danuta Bukowska, Nicolaus Copernicus Univ. (Poland)
Maciej Szkulmowski, Nicolaus Copernicus Univ. (Poland)
Jakub Wlodarczyk, Nencki Institute of Experimental Biology (Poland)
Karol Karnowski, Nicolaus Copernicus Univ. (Poland)
Daniel Ruminski, Nicolaus Copernicus Univ. (Poland)
Andrzej Kowalczyk, Nicolaus Copernicus Univ. (Poland)
Maciej Wojtkowski, Nicolaus Copernicus Univ. (Poland)


Published in SPIE Proceedings Vol. 7883:
Photonic Therapeutics and Diagnostics VII
Kenton W. Gregory; Guillermo J. Tearney; Laura Marcu; Nikiforos Kollias; Bernard Choi; Haishan Zeng; Andreas Mandelis; Henry Hirschberg; Steen J. Madsen; Hyun Wook Kang; Bodo E. Knudsen; Anita Mahadevan-Jansen; E. Duco Jansen; Brian Jet-Fei Wong; Justus F. R. Ilgner, Editor(s)

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