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Proceedings Paper

Electrical stimulation of peripheral nerves induces optical responses via skeletal muscle kinematics
Author(s): M. Kelley Erb; Debbie K. Chen; Angelo Sassaroli; Sergio Fantini; Peter R. Bergethon
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Paper Abstract

We have previously reported an optical response in human subjects occurring at 100 ms following electrical stimulation of peripheral nerves. In the present study, an animal model has been created to directly investigate the myogenic components of the signal. In addition, experiments have been performed in human subjects to investigate the signal's neuroanatomical specificity, sensitivity to muscle motion, and spatial and spectral features. The results of this work suggest that the observed optical signal derives from stimulus-induced motion associated with muscle contraction and likely contains myological information of clinical value.

Paper Details

Date Published: 2 March 2011
PDF: 12 pages
Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 789609 (2 March 2011); doi: 10.1117/12.875145
Show Author Affiliations
M. Kelley Erb, Boston Univ. School of Medicine (United States)
Debbie K. Chen, Tufts Univ. (United States)
Angelo Sassaroli, Tufts Univ. (United States)
Sergio Fantini, Tufts Univ. (United States)
Peter R. Bergethon, Boston Univ. School of Medicine (United States)

Published in SPIE Proceedings Vol. 7896:
Optical Tomography and Spectroscopy of Tissue IX
Bruce Jason Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

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