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Proceedings Paper

Integrated optical coherence tomography - ultrasound system and miniaturized probes for intravascular imaging
Author(s): Jiechen Yin; Xiang Li; Joe Jing; Changhong Hu; Qifa Zhou; Tanya Burney; David Mukai; Sari Mahon; Ahmad Edris; Khiet Hoang; K. Kirk Shung; Matthew Brenner; Jagat Narula; Zhongping Chen
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Paper Abstract

We report on the development of a multimodal optical coherence tomography (OCT) - ultrasound (US) system and miniaturized OCT-US probe for intravascular imaging. Both OCT optical components and a US transducer were integrated into a single probe, enabling both OCT and US imaging at the same time. A miniaturized OCT-US probe using a single element transducer was designed with a maximum outer diameter of 0.8 mm, which is suitable for in vivo intravascular imaging. The integrated OCT-US imaging system adopted a two-channel data acquisition card to digitize both OCT and US signals. Simultaneous OCT and US data processing and image display were also achieved using our home-developed software. In vitro OCT and US imaging of human aortic tissue was performed using this multimodal imaging system, which demonstrated the feasibility of the OCT-US system in intravascular imaging and its potential in detection of atherosclerotic plaques.

Paper Details

Date Published: 16 February 2011
PDF: 4 pages
Proc. SPIE 7889, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV, 788918 (16 February 2011); doi: 10.1117/12.875128
Show Author Affiliations
Jiechen Yin, Univ. of California, Irvine (United States)
Xiang Li, The Univ. of Southern California (United States)
Joe Jing, Beckman Laser Institute (United States)
Changhong Hu, The Univ. of Southern California (United States)
Qifa Zhou, The Univ. of Southern California (United States)
Tanya Burney, Beckman Laser Institute (United States)
David Mukai, Beckman Laser Institute (United States)
Sari Mahon, Beckman Laser Institute (United States)
Ahmad Edris, Univ. of California, Irvine Medical Ctr. (United States)
Khiet Hoang, Univ. of California, Irvine Medical Ctr. (United States)
K. Kirk Shung, The Univ. of Southern California (United States)
Matthew Brenner, Univ. of California, Irvine Medical Ctr. (United States)
Jagat Narula, Univ. of California, Irvine Medical Ctr. (United States)
Zhongping Chen, Beckman Laser Institute (United States)


Published in SPIE Proceedings Vol. 7889:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

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