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Proceedings Paper

Temperature increase of ex vivo corneas from multiple 2.01-micron incident laser pulses
Author(s): Edward Kelly; Thomas Johnson
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Paper Abstract

Current laser safety standards for multiple pulse lasers are based primarily on modeling and the results of single pulse studies. Previous thermal effects studies have focused on histological and visible endpoints, with only a few studies examining the actual temperatures achieved. The goal of this research was to probe the actual vertical temperature profile produced by 2.01 micron laser pulses in the cornea. In this study the corneal temperature rise from multiple 2.01 micron Tm:YAG laser pulses was investigated using ex-vivo rabbit eyes. A thermal-measurement data set for a different number of pulses was collected and compared. An infrared thermal camera employing microbolometer detectors captured surface temperature rises resulting from laser pulses. Single 10 ms pulses as well as two, three, and four pulse sequences were utilized while the total energy delivered was held constant. A comparison of the data to temperatures required for denaturing proteins and the current laser safety guidelines will be presented.

Paper Details

Date Published: 18 February 2011
PDF: 14 pages
Proc. SPIE 7897, Optical Interactions with Tissue and Cells XXII, 78970J (18 February 2011); doi: 10.1117/12.874894
Show Author Affiliations
Edward Kelly, Colorado State Univ. (United States)
Thomas Johnson, Colorado State Univ. (United States)

Published in SPIE Proceedings Vol. 7897:
Optical Interactions with Tissue and Cells XXII
E. Duco Jansen; Robert J. Thomas, Editor(s)

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