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Proceedings Paper

Effect of timolol on sub-foveal choroidal blood flow using laser Doppler flowmetry
Author(s): Nithiyanantham Palanisamy; Luigi Rovati; Mauro Cellini; Corrado Gizzi; Ernesto Strobbe; Emilio Campos; Charles E. Riva
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Paper Abstract

Laser Doppler flowmetry (LDF) is a technique used to measure relative average velocity, number and flux (number times velocity) of red blood cells in vessels or capillaries. In this study, the effect of topical timolol on the choroidal circulation was investigated in 12 healthy subjects. Maximum velocity of red blood cells and volumetric blood flow rate in sub-foveal choroids are determined in each eye just before instillation of drops and then every 30 min upto 2 hours. Average intraocular pressure (IOP) decreased significantly in the timolol-treated eyes compared to that of placebo-treated eyes. Nevertheless no significant differences in choroidal blood hemodynamic between timolol and placebo-treated eyes were observed.

Paper Details

Date Published: 11 February 2011
PDF: 9 pages
Proc. SPIE 7885, Ophthalmic Technologies XXI, 78850E (11 February 2011); doi: 10.1117/12.874495
Show Author Affiliations
Nithiyanantham Palanisamy, Univ. degli Studi di Modena e Reggio Emilia (Italy)
Luigi Rovati, Univ. degli Studi di Modena e Reggio Emilia (Italy)
Mauro Cellini, Univ. degli Studi di Bologna (Italy)
Corrado Gizzi, Univ. degli Studi di Bologna (Italy)
Ernesto Strobbe, Univ. degli Studi di Bologna (Italy)
Emilio Campos, Univ. degli Studi di Bologna (Italy)
Charles E. Riva, Univ. of Lausanne (Switzerland)


Published in SPIE Proceedings Vol. 7885:
Ophthalmic Technologies XXI
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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