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Proceedings Paper

Modification of a long period grating-based fiber optic for DNA biosensing
Author(s): M. Sozzi; A. Cucinotta; R. Corradini; R. Marchelli; M. Konstantaki; S. Pissadakis; S. Selleri
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Paper Abstract

The feasibility of a biosensor for DNA label-free detection, based on long period fiber gratings, has been investigated. The surface of the grating has been functionalized with Peptide Nucleic Acid (PNA) probes. DNA strands, matched with the PNA probes, have been immobilized on the surface itself. The possibility of a resonant wavelength shift in the transmission spectrum due to the DNA capture will be discussed. The problem of reusing the sensor for multiple measurements will also be addressed.

Paper Details

Date Published: 17 February 2011
PDF: 6 pages
Proc. SPIE 7894, Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI, 78940J (17 February 2011); doi: 10.1117/12.874458
Show Author Affiliations
M. Sozzi, Univ. of Parma (Italy)
A. Cucinotta, Univ. of Parma (Italy)
R. Corradini, Univ. of Parma (Italy)
R. Marchelli, Univ. of Parma (Italy)
M. Konstantaki, Foundation for Research and Technology-Hellas (Greece)
S. Pissadakis, Foundation for Research and Technology-Hellas (Greece)
S. Selleri, Univ. of Parma (Italy)


Published in SPIE Proceedings Vol. 7894:
Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI
Israel Gannot, Editor(s)

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