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Proceedings Paper

Influence of laser and LED irradiation on mast cells of cutaneous wounds of rats with iron deficiency anemia
Author(s): Cristiane Becher Rosa; Susana C. P. Oliveira Sampaio; Juliana S. C. Monteiro; Maria F. L. Ferreira; Fátima A. A. Zanini; Jean N. Santos; Maria Cristina T. Cangussú; Antonio L. B. Pinheiro
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Paper Abstract

This work aimed to study histologically the effect of Laser or LED phototherapy on mast cells on cutaneous wounds of rats with iron deficiency. 18 rats were used and fed with special peleted iron-free diet. An excisional wound was created on the dorsum of each animal which were divided into: Group I - Control with anemia + no treatment; Group II - Anemia + Laser; Group III - Anemia + LED; Group IV - Healthy + no treatment; Group V - Healthy + Laser; Group VI - Healthy + LED. Irradiation was performed using a diode Laser (λ660nm, 40mW, CW, total dose of 10J/cm2, 4X2.5J/cm2) or a RED-LED ( λ700nm, 15mW, CW, total dose of 10J/cm2). Histological specimens were routinely processed, cut and stained with toluidine blue and mast cell counts performed. No significant statistic difference was found between groups as to the number of degranulated, non-degradulated or total mast cells. Greater mean values were found for degranulated mast cells in the Anemia + LED. LED irradiation on healthy specimens resulted in a smaller number of degranulated mast cells. Our results leads to conclude that there are no significant differences in the number of mast cells seven days after irradiation following Laser or LED phototherapy.

Paper Details

Date Published: 17 February 2011
PDF: 6 pages
Proc. SPIE 7887, Mechanisms for Low-Light Therapy VI, 78870S (17 February 2011); doi: 10.1117/12.874223
Show Author Affiliations
Cristiane Becher Rosa, Federal Univ. of Bahia (Brazil)
Susana C. P. Oliveira Sampaio, Federal Univ. of Bahia (Brazil)
Juliana S. C. Monteiro, Federal Univ. of Bahia (Brazil)
Maria F. L. Ferreira, Federal Univ. of Alagoas (Brazil)
Fátima A. A. Zanini, Brugnera & Zanin Institute (Brazil)
Jean N. Santos, Federal Univ. of Bahia (Brazil)
Maria Cristina T. Cangussú, Federal Univ. of Bahia (Brazil)
Antonio L. B. Pinheiro, Federal Univ. of Bahia (Brazil)
Camilo Castelo Branco Univ. (Brazil)
National Institute of Optics and Photonics (Brazil)


Published in SPIE Proceedings Vol. 7887:
Mechanisms for Low-Light Therapy VI
Michael R. Hamblin; Ronald W. Waynant; Juanita Anders, Editor(s)

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