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Proceedings Paper

Fast semi-analytical acoustic inversion for quantitative optoacoustic tomography
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Paper Abstract

We present a fast inversion algorithm for quantitative two- and three-dimensional optoacoustic tomography. The algorithm is based on an accurate and efficient forward model, which eliminates the need for regularization in the inversion and can achieve real-time performance. The reconstruction speed and other algorithmic performances are demonstrated using numerical simulation studies and experimentally on tissue-mimicking optically heterogeneous phantoms and small animals. In the experimental examples, the model-based reconstructions manifested correctly the effect of light attenuation through the objects and did not suffer from the artifacts which usually afflict the commonly used filtered backprojection algorithms, such as negative absorption values.

Paper Details

Date Published: 19 February 2011
PDF: 11 pages
Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 78992R (19 February 2011); doi: 10.1117/12.874048
Show Author Affiliations
Amir Rosenthal, Univ. of München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Thomas Jetzfellner, Univ. of München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Daniel Razansky, Univ. of München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Vasilis Ntziachristos, Univ. of München (Germany)
Helmholtz Zentrum München GmbH (Germany)


Published in SPIE Proceedings Vol. 7899:
Photons Plus Ultrasound: Imaging and Sensing 2011
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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