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Proceedings Paper

Properties of end-expiratory breath hold responses measured with near-infrared spectroscopy
Author(s): Jaakko Virtanen; Tommi Noponen; Risto J. Ilmoniemi
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Paper Abstract

Near-infrared spectroscopy (NIRS) can be used to assess the cerebrovascular response to breath hold. We measured eight healthy subjects during voluntary end-expiratory breath hold to study inter- and intraindividual variability of the deoxy- (HbR) and oxyhemoglobin (HbO2) response curves for the scalp and cerebral cortex. Although cortical [HbO2] behaves qualitatively similarly in all subjects, there is large inter- and intraindividual variability, and in the case of [HbR] also qualitative variability. However, the linearity of [HbO2] increase during the breath hold has encouraging measurement repeatability, and it may even indicate an individual's CO2 tolerance. This result may help understand why breath hold duration varies between subjects more than the total [HbO2] increase during breath hold.

Paper Details

Date Published: 17 February 2011
PDF: 10 pages
Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 78960D (17 February 2011); doi: 10.1117/12.873743
Show Author Affiliations
Jaakko Virtanen, Aalto Univ. (Finland)
Helsinki Univ. Hospital (Finland)
Tommi Noponen, Turku Univ. Hospital (Finland)
Risto J. Ilmoniemi, Aalto Univ. (Finland)


Published in SPIE Proceedings Vol. 7896:
Optical Tomography and Spectroscopy of Tissue IX
Bruce Jason Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

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