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Proceedings Paper

Monte Carlo simulation of non-invasive glucose measurement based on FMCW LIDAR
Author(s): Bing Xiong; Wenxiong Wei; Nan Liu; Jian-Jun He
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Paper Abstract

Continuous non-invasive glucose monitoring is a powerful tool for the treatment and management of diabetes. A glucose measurement method, with the potential advantage of miniaturizability with no moving parts, based on the frequency modulated continuous wave (FMCW) LIDAR technology is proposed and investigated. The system mainly consists of an integrated near-infrared tunable semiconductor laser and a detector, using heterodyne technology to convert the signal from time-domain to frequency-domain. To investigate the feasibility of the method, Monte Carlo simulations have been performed on tissue phantoms with optical parameters similar to those of human interstitial fluid. The simulation showed that the sensitivity of the FMCW LIDAR system to glucose concentration can reach 0.2mM. Our analysis suggests that the FMCW LIDAR technique has good potential for noninvasive blood glucose monitoring.

Paper Details

Date Published: 9 November 2010
PDF: 6 pages
Proc. SPIE 7845, Optics in Health Care and Biomedical Optics IV, 784518 (9 November 2010); doi: 10.1117/12.870348
Show Author Affiliations
Bing Xiong, Zhejiang Univ. (China)
Wenxiong Wei, Zhejiang Univ. (China)
Nan Liu, Zhejiang Univ. (China)
Jian-Jun He, Zhejiang Univ. (China)


Published in SPIE Proceedings Vol. 7845:
Optics in Health Care and Biomedical Optics IV
Qingming Luo; Ying Gu; Xingde Li, Editor(s)

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