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Proceedings Paper

Evaluation of whole blood coagulation process by optical coherence tomography
Author(s): Xiangqun Xu; Jia Lin
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Paper Abstract

This study was to investigate the feasibility of using optical coherence tomography (OCT) to evaluate whole blood coagulation process. Attenuation coefficients and 1/e light penetration depth (D1/e) against time of human whole blood during in vitro clot formation under static were measured from the OCT profiles of reflectance vs depth. The results obtained clearly showed that the optical parameters are able to identify three stages during the in vitro blood clotting process. It is concluded that D1/e measured by OCT is a potential parameter to quantify and follow the liquid-gel transition of blood during clotting.

Paper Details

Date Published: 8 November 2010
PDF: 7 pages
Proc. SPIE 7845, Optics in Health Care and Biomedical Optics IV, 784508 (8 November 2010); doi: 10.1117/12.869904
Show Author Affiliations
Xiangqun Xu, Zhejiang Sci-Tech Univ. (China)
Jia Lin, Zhejiang Sci-Tech Univ. (China)

Published in SPIE Proceedings Vol. 7845:
Optics in Health Care and Biomedical Optics IV
Qingming Luo; Ying Gu; Xingde Li, Editor(s)

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