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Proceedings Paper

Short thio-multi-walled carbon nanotubes and Au nanoparticles enhanced electrochemical DNA biosensor for DNA hybridization detection
Author(s): Feng Guo; Jimei Zhang; Zhao Dai; Guo Zheng
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Paper Abstract

A novel and sensitive electrochemical DNA biosensor based on multi-walled carbon nanotubes functionalized with a thio group (MWNTs-SH) and gold nanoparticles (GNPs) for covalent DNA immobilization and enhanced hybridization detection is described. The key step for developing this novel DNA biosensor is to cut the pristine MWNT into short and generate lots of active sites simultaneously. With this approach, the target DNA could be quantified in a linear range from 8.5×10-10 to 1.5×10-5 mol/L, with a detection limit of 1.67×10-11 mol/L by 3σ.

Paper Details

Date Published: 21 July 2010
PDF: 5 pages
Proc. SPIE 7749, 2010 International Conference on Display and Photonics, 77490H (21 July 2010); doi: 10.1117/12.869660
Show Author Affiliations
Feng Guo, Tianjin Polytechnic Univ. (China)
Jimei Zhang, Tianjin Polytechnic Univ. (China)
Zhao Dai, Tianjin Polytechnic Univ. (China)
Guo Zheng, Tianjin Polytechnic Univ. (China)


Published in SPIE Proceedings Vol. 7749:
2010 International Conference on Display and Photonics

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