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Proceedings Paper

Photodynamic therapy for port wine stains assisted by a novel robotic system
Author(s): Naiyan Huang; Jianguo Zhu; Ying Wang; Guibin Bian; Xingguang Duan; Weifeng Liu; Xiaoying Tang; Xingtao Wang; Shihu Cui; Chunyu Zhang; Ying Gu
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Paper Abstract

Port wine stains (PWS) is a vascular malformation consisting of dilated capillaries in the superficial dermis. Photodynamic therapy (PDT) is an effective approach in the treatment of PWS. However, the procedure of treatment is a low efficient and hard work, as the doctor need to hold laser fiber to irradiate for 20 min to 50 min per lesion. So an assisted novel robotic system was developed to instead part of doctor's work. The robotic system consisted of 7 degrees of freedom, in which there were 5 passive joints and 2 active joints. Binocular surveillance system was used as guidance for the robot. Clinical trial compared 20 patients (38 lesions) treated by the robotic system with another 20 patients (38 lesions) treated by a doctor. The patients in both groups were injected intravenously with photosensitizer (PSD-007, 4-5mg/kg) and irradiated with 532 nm laser (100mW/cm2, 120-300J/cm2) immediately. Both groups had same good therapeutic results. The robotic system is helpful in the PWS-PDT and hopefully would become a part of PWS therapy machine in the future.

Paper Details

Date Published: 8 November 2010
PDF: 7 pages
Proc. SPIE 7845, Optics in Health Care and Biomedical Optics IV, 78451G (8 November 2010); doi: 10.1117/12.868888
Show Author Affiliations
Naiyan Huang, Chinese PLA General Hospital (China)
Jianguo Zhu, Chinese PLA General Hospital (China)
Ying Wang, Chinese PLA General Hospital (China)
Guibin Bian, Beijing Institute of Technology (China)
Xingguang Duan, Beijing Institute of Technology (China)
Weifeng Liu, Beijing Institute of Technology (China)
Xiaoying Tang, Beijing Institute of Technology (China)
Xingtao Wang, Beijing Institute of Technology (China)
Shihu Cui, Beijing Institute of Technology (China)
Chunyu Zhang, Beijing Institute of Technology (China)
Ying Gu, Chinese PLA General Hospital (China)


Published in SPIE Proceedings Vol. 7845:
Optics in Health Care and Biomedical Optics IV
Qingming Luo; Ying Gu; Xingde Li, Editor(s)

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