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Proceedings Paper

The analysis of aging skin based on multiphoton microscopy
Author(s): Shulian Wu; Hui Li; Xiaoman Zhang; Zhifang Li; Shufei Xu
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Paper Abstract

Aging is a very important issue not only in dermatology, but also in cosmetic science. Cutaneous aging involves both chronological and photoaging aging process. The chronological aging is induced with the passage of time. And the photoaging skin is the extrinsic aging caused by sun exposure. The aim of this study is to use multiphoton microscopy (MPM) in vivo to assess intrinsic-age-related and photo-age-related difference. The changes of dermal collagen are measured in quantitively. The algorithm that we used automatically produced the transversal dermal map from MPM. Others, the texture of dermis are analyzed by Fourier transform and Gray Level Co-occurrence Matrix. And the object extraction in textured images is proposed based on the method in object edge extraction, and the aim of it is to detect the object hidden in the skin texture in difference aging skin. The result demonstrates that the approach is effective in detecting the object in epidermis and dermis textured image in different aging skin. It could help to further understand the aging mechanism.

Paper Details

Date Published: 8 November 2010
PDF: 8 pages
Proc. SPIE 7845, Optics in Health Care and Biomedical Optics IV, 78450S (8 November 2010); doi: 10.1117/12.868879
Show Author Affiliations
Shulian Wu, Fujian Normal Univ. (China)
Hui Li, Fujian Normal Univ. (China)
Xiaoman Zhang, Fujian Normal Univ. (China)
Zhifang Li, Fujian Normal Univ. (China)
Shufei Xu, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 7845:
Optics in Health Care and Biomedical Optics IV
Qingming Luo; Ying Gu; Xingde Li, Editor(s)

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