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Proceedings Paper

Optical fiber biosensor based on enzymatic coating matrix for catecholamines assessment in human urine
Author(s): Lurdes I. B. Silva; Ana C. Freitas; Teresa A. P. Rocha-Santos; M. E. Pereira; Armando C. Duarte
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Paper Abstract

An optical fiber (OF) biosensor has been developed and applied for simultaneous determination of catecholamines (dopamine, norepinephrine and epinephrine) in human urine. The developed analytical device shows a high potential for catecholamines quantification with a detection limit of 2.1, 2.6 and 3.4 pg mL-1 for dopamine, norepinephrine and epinephrine, respectively. The analytical performance of the OF biosensor was found to be similar to that of the High Performance Liquid Chromatography - Electrochemical Detector (HPLC-ED) regarding catecholamines determination in samples of human urine.

Paper Details

Date Published: 8 September 2010
PDF: 4 pages
Proc. SPIE 7653, Fourth European Workshop on Optical Fibre Sensors, 76531I (8 September 2010); doi: 10.1117/12.865820
Show Author Affiliations
Lurdes I. B. Silva, Instituto Piaget (Portugal)
Univ. de Aveiro (Portugal)
Ana C. Freitas, Instituto Piaget (Portugal)
Teresa A. P. Rocha-Santos, Instituto Piaget (Portugal)
M. E. Pereira, Univ. de Aveiro (Portugal)
Armando C. Duarte, Univ. de Aveiro (Portugal)


Published in SPIE Proceedings Vol. 7653:
Fourth European Workshop on Optical Fibre Sensors
José Luís Santos; Brian Culshaw; José Miguel López-Higuera; William N. MacPherson, Editor(s)

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