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Proceedings Paper

Detection of swine-origin influenza A (H1N1) viruses using a paired surface plasma waves biosensor
Author(s): Li-Chen Su; Ying-Feng Chang; Ying-Chang Li; Jo-Ping Hsieh; Cheng-Chung Lee; Chien Chou
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Paper Abstract

In order to enhance the sensitivity of conventional rapid test technique for the detection of swine-origin influenza A (H1N1) viruses (S-OIVs), we used a paired surface plasma waves biosensor (PSPWB) based on SPR in conjunction with an optical heterodyne technique. Experimentally, PSPWB showed a 125-fold improvement at least in the S-OIV detection as compared to conventional enzyme linked immunosorbent assay. Moreover, the detection limit of the PSPWB for the S-OIV detection was enhanced 250-fold in buffer at least in comparison with that of conventional rapid influenza diagnostic test.

Paper Details

Date Published: 19 August 2010
PDF: 6 pages
Proc. SPIE 7759, Biosensing III, 775905 (19 August 2010); doi: 10.1117/12.863622
Show Author Affiliations
Li-Chen Su, National Central Univ. (Taiwan)
Chang Gung Univ. (Taiwan)
Ying-Feng Chang, Chang Gung Univ. (Taiwan)
National Yang-Ming Univ. (Taiwan)
Ying-Chang Li, National Central Univ. (Taiwan)
Chang Gung Univ. (Taiwan)
Jo-Ping Hsieh, Chang Gung Univ. (Taiwan)
National Yang-Ming Univ. (Taiwan)
Cheng-Chung Lee, National Central Univ. (Taiwan)
Chien Chou, National Central Univ. (Taiwan)
Chang Gung Univ. (Taiwan)
National Yang-Ming Univ. (Taiwan)


Published in SPIE Proceedings Vol. 7759:
Biosensing III
Hooman Mohseni; Manijeh Razeghi, Editor(s)

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