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Proceedings Paper

Local plasmonic resonance based biosensor for investigating DNA hybridization using ellipsometry
Author(s): Rakesh Singh Moirangthem; Yia-Chung Chang; Pei-Kuen Wei
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Paper Abstract

A label free, non-destructive and high sensitivity biosensor with sub-nanometer thickness resolution is presented. We investigate various sequences of DNA attached on gold nanoparticles (AuNPs) on top of a layer of self assembling molecules. A strategy to amplify localized surface plasmon resonance (LSPR) response is made by sandwiching DNA sequences between two AuNPs. We monitor the induced changes in polarization state or phase of reflected light from the surface as a function of the photon energy as a sensor signal by using ellipsometry and compare that with theoretical simulation.

Paper Details

Date Published: 10 September 2010
PDF: 7 pages
Proc. SPIE 7757, Plasmonics: Metallic Nanostructures and Their Optical Properties VIII, 77573J (10 September 2010); doi: 10.1117/12.862921
Show Author Affiliations
Rakesh Singh Moirangthem, Research Ctr. for Applied Sciences (Taiwan)
National Tsing Hua Univ. (Taiwan)
Yia-Chung Chang, Research Ctr. for Applied Sciences (Taiwan)
Pei-Kuen Wei, Research Ctr. for Applied Sciences (Taiwan)


Published in SPIE Proceedings Vol. 7757:
Plasmonics: Metallic Nanostructures and Their Optical Properties VIII
Mark I. Stockman, Editor(s)

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