Share Email Print
cover

Proceedings Paper

Nanostructured porous silicon-based dual luminescent/magnetic particles for biomedical tracking
Author(s): A. Muñoz-Noval; V. Sanchez Vaquero; V. Torres-Costa; D. Gallach; V. Ferro-Llanos; J. J. Serrano; F. del Pozo; M. Manso-Silván; J. P. Garcia Ruiz; R. J. Martín-Palma
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Nanostructured porous silicon (nanoPS) particles with dual luminescent and magnetic properties have been fabricated and biofunctionalized aiming at cellular applications in both progenitor cell research and cellular therapy. The dual luminescent/magnetic nanoparticles (DLMNPs) have been fabricated by the electrodeposition of cobalt and iron into nanoPS. DLMNPs show luminescence properties as illustrated by photoluminescence measurements and direct fluorescence microscopy, and simultaneously exhibit magnetic properties. The resulting DLMNPs have been subsequently functionalized and internalized into cells. The experimental results show that luminescence remains several days and corroborate the biocompatibility of the DLMNPs. Such dual properties are relevant research tools as non toxic cellular tracker for progenitor cells and consequently able to be used in many strategies of cellular therapy. Additionally, the nanoPS-DLMNPs can be functionalized with various biomolecules that will provide them with new functionalities.

Paper Details

Date Published: 24 August 2010
PDF: 8 pages
Proc. SPIE 7766, Nanostructured Thin Films III, 77660P (24 August 2010); doi: 10.1117/12.859896
Show Author Affiliations
A. Muñoz-Noval, CIBER-BBN (Spain)
Univ. Autónoma de Madrid (Spain)
V. Sanchez Vaquero, CIBER-BBN (Spain)
Univ. Autónoma de Madrid (Spain)
V. Torres-Costa, CIBER-BBN (Spain)
Univ. Autónoma de Madrid (Spain)
D. Gallach, CIBER-BBN (Spain)
Univ. Autónoma de Madrid (Spain)
V. Ferro-Llanos, CIBER-BBN (Spain)
Univ. Politécnica de Madrid (Spain)
J. J. Serrano, CIBER-BBN (Spain)
Univ. Politécnica de Madrid (Spain)
F. del Pozo, CIBER-BBN (Spain)
Univ. Politécnica de Madrid (Spain)
M. Manso-Silván, CIBER-BBN (Spain)
Univ. Autónoma de Madrid (Spain)
J. P. Garcia Ruiz, CIBER-BBN (Spain)
Univ. Politécnica de Madrid (Spain)
R. J. Martín-Palma, CIBER-BBN (Spain)
Univ. Autónoma de Madrid (Spain)


Published in SPIE Proceedings Vol. 7766:
Nanostructured Thin Films III
Raúl J. Martin-Palma; Yi-Jun Jen; Akhlesh Lakhtakia, Editor(s)

© SPIE. Terms of Use
Back to Top