Share Email Print
cover

Proceedings Paper

Photodynamic therapy influence on anti-cancer immunity
Author(s): O. G. Isaeva; V. A. Osipov
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

The system of partial differential equations describing tumor-immune dynamics with angiogenesis taken into account is presented. For spatially homogeneous case, the steady state analysis of the model is carried out. The effects of single photodynamic impact are numerically simulated. In the case of strong immune response we found that the photodynamic therapy (PDT) gives rise to the substantial shrinkage of tumor size which is accompanied by the increase of IL-2 concentration. On the contrary, the photodynamic stimulation of weak immune response is shown to be insufficient to reduce the tumor. These findings indicate the important role of anti-cancer immune response in the long-term tumor control after PDT.

Paper Details

Date Published: 11 February 2010
PDF: 9 pages
Proc. SPIE 7547, Saratov Fall Meeting 2009: International School for Junior Scientists and Students on Optics, Laser Physics, and Biophotonics, 754704 (11 February 2010); doi: 10.1117/12.853588
Show Author Affiliations
O. G. Isaeva, Joint Institute for Nuclear Research (Russian Federation)
V. A. Osipov, Joint Institute for Nuclear Research (Russian Federation)


Published in SPIE Proceedings Vol. 7547:
Saratov Fall Meeting 2009: International School for Junior Scientists and Students on Optics, Laser Physics, and Biophotonics
Valery V. Tuchin; Elina A. Genina, Editor(s)

© SPIE. Terms of Use
Back to Top