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Proceedings Paper

Fluorescence sensing of biological tissue structures using Mn-doped CdS nanoparticles as biomarkers
Author(s): Volodymyr I. Fediv; Andriy I. Savchuk; Galyna Yu. Rudko; Igor S. Davydenko; Tetyana A. Savchuk; Evgeniy G. Gule; Svitlana A. Ivanchak
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Paper Abstract

The present paper describes the growth, absorption and photoluminescence spectra of Mn-doped cadmium sulfide nanoparticles, and application of nanoparticles for cellular imaging. Formation of CTAB-coated CdS:Mn nanoparticles is monitored by optical methods. The optical absorption edge of CdS:Mn nanoparticles is shifted to the higher-energy side as compared to bulk crystals due to the quantum confinement effect. TEM images demonstrate that the average size of CdS:Mn nanoparticles embedded into gelatin matrix is larger than the one of CTAB-coated nanoparticles. The changes of the optical density during the process of the nanoparticles growth are attributed to the increase of their density in the solution. The effects of coverage layer in the PL properties nanosensors are studied by the photoluminescence method. Interactions between CdS:Mn NPs and organic molecules are probed by photoluminescence method, and the results obtained are used for identification of the Kupffer's cells in the histologic specimens of liver.

Paper Details

Date Published: 31 December 2009
PDF: 7 pages
Proc. SPIE 7388, Ninth International Conference on Correlation Optics, 73880Y (31 December 2009); doi: 10.1117/12.853345
Show Author Affiliations
Volodymyr I. Fediv, Bukovinian State Medical Univ. (Ukraine)
Andriy I. Savchuk, Yuriy Fedkovych Chernivtsi National Univ. (Ukraine)
Galyna Yu. Rudko, V.E. Lashkaryev Institute of Semiconductor Physics (Ukraine)
Igor S. Davydenko, Bukovinian State Medical Univ. (Ukraine)
Tetyana A. Savchuk, Yuriy Fedkovych Chernivtsi National Univ. (Ukraine)
Evgeniy G. Gule, V.E. Lashkaryev Institute of Semiconductor Physics (Ukraine)
Svitlana A. Ivanchak, Yuriy Fedkovych Chernivtsi National Univ. (Ukraine)


Published in SPIE Proceedings Vol. 7388:
Ninth International Conference on Correlation Optics

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