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Proceedings Paper

The measurement of hemoglobin oxygen saturation using multiwavelength photoacoustic microscopy
Author(s): Zilin Deng; Xiaoquan Yang; Lejun Yu; Hui Gong
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Paper Abstract

Hemoglobin oxygen saturation (SO2) is one of the most critical functional parameters to the metabolism. In this paper, we mainly introduced some initial results of measuring blood oxygen using multi-wavelength photoacoustic microscopy (PAM). In phantom study, we demonstrate the photoacoustic signal amplitude increases linearly with the concentration of red or blue ink. Then the calculated concentration of red ink in double-ink mixtures with PAM has a 5% difference with the result measured with spectrophotometric analysis. In ex vivo experiment, the measured result exhibt 15% difference between the PAM and spectrophotometric analysis. Experiment results suggest that PAM could be used to determine the SO2 quantitatively.

Paper Details

Date Published: 12 February 2010
PDF: 8 pages
Proc. SPIE 7547, Saratov Fall Meeting 2009: International School for Junior Scientists and Students on Optics, Laser Physics, and Biophotonics, 75470C (12 February 2010); doi: 10.1117/12.853222
Show Author Affiliations
Zilin Deng, Huazhong Univ. of Science and Technology (China)
Xiaoquan Yang, Huazhong Univ. of Science and Technology (China)
Lejun Yu, Huazhong Univ. of Science and Technology (China)
Hui Gong, Huazhong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 7547:
Saratov Fall Meeting 2009: International School for Junior Scientists and Students on Optics, Laser Physics, and Biophotonics

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