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Proceedings Paper

Hybrid nano plasmonics for integrated biosensor
Author(s): Chii-Wann Lin; Jun-Haw Lee; Nan-Fu Chiu; Szu-Yuan Lee; Kou-Chen Liu; Feng-Yu Tsai; Chia-Yu Yen; Chun-Nan Lee
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Paper Abstract

SPR biosensor with OLED and nano-grating for HBV LAMP product detection is reported. Directional emissions by grating-coupler match the resonant condition of SP modes. Concentration changes result in color shift at specific angle. Real time detection of virus load down to 5 copies/25 ul can be achieved in 30 minutes. Surface plasmon Resonant (SPR) biosensor has been used for quantitative measurement of molecular interactions for its advantages of high sensitivity, label-free and real-time detection. In this paper, we report recent efforts on further enhancement of SPR biosensors by the heterogeneous integration of organic electroluminescence light source and nano-grating structure for the feasibility study on the fast and high sensitivity detection of HBV isothermal amplification products, Mg2P2O7. We demonstrated the surface plasmon coupled through hybrid nano-grating structure has highly directional emissions corresponding to the resonant condition of surface plasmon modes on the Au/air interface and controllable plasmonics band-gap by pitch modulation. SPGCE resulted in color change from yellowish green to orange at a certain viewing angle, when contacting glucose with concentration increasing from 10 to 40%.

Paper Details

Date Published: 1 December 2009
PDF: 6 pages
Proc. SPIE 7634, Optical Sensors and Biophotonics, 76340O (1 December 2009); doi: 10.1117/12.853214
Show Author Affiliations
Chii-Wann Lin, National Taiwan Univ. (Taiwan)
Jun-Haw Lee, National Taiwan Univ. (Taiwan)
Nan-Fu Chiu, National Taiwan Univ. (Taiwan)
Szu-Yuan Lee, National Taiwan Univ. (Taiwan)
Kou-Chen Liu, Chang-Gung Univ. (Taiwan)
Feng-Yu Tsai, National Taiwan Univ. (Taiwan)
Chia-Yu Yen, National Taiwan Univ. (Taiwan)
Chun-Nan Lee, National Taiwan Univ. (Taiwan)

Published in SPIE Proceedings Vol. 7634:
Optical Sensors and Biophotonics
Xingde Li; Qingming Luo; Vasilis Ntziachristos; Yoshiaki Yasuno, Editor(s)

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