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Proceedings Paper

Clinical diagnosis of oral submucous fibrosis with optical coherence tomography
Author(s): Cheng-Kuang Lee; Meng-Tsan Tsai; C. C. Yang; Chun-Pin Chiang
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Paper Abstract

A swept-source optical coherence tomography (SS-OCT) system with a specially designed probe is built for clinical scanning of oral submucous fibrosis (OSF) patients. By analysing 44 OSF cases of SS-OCT scanning results, two indicators, including epithelium (EP) thickness and standard deviation (SD) of A-mode scan intensity in the laminar propria (LP) layer, are found useful for real-time OSF diagnosis. Statistics show that sensitivity and specificity of LP SD can reach 84.1 and 95.5 %, respectively. Also, both sensitivity and specificity of EP thickness can reach 100 %.

Paper Details

Date Published: 25 November 2009
PDF: 8 pages
Proc. SPIE 7634, Optical Sensors and Biophotonics, 763405 (25 November 2009); doi: 10.1117/12.852410
Show Author Affiliations
Cheng-Kuang Lee, National Taiwan Univ. (Taiwan)
Meng-Tsan Tsai, National Taiwan Univ. (Taiwan)
C. C. Yang, National Taiwan Univ. (Taiwan)
Chun-Pin Chiang, National Taiwan Univ. (Taiwan)


Published in SPIE Proceedings Vol. 7634:
Optical Sensors and Biophotonics
Xingde Li; Qingming Luo; Vasilis Ntziachristos; Yoshiaki Yasuno, Editor(s)

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