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Proceedings Paper

Functional common-path Fourier-domain OCT for hemoglobin oxygen saturation imaging
Author(s): Xuan Liu; Jin U Kang
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Paper Abstract

In this paper, we propose and investigate a technique to deduce hemoglobin oxygen saturation (SO2) variation image using Spectroscopic Optical Coherence Tomography (OCT). The technique is based on Morlet wavelet transformation and make use of the different absorption properties of hemoglobin (Hb) and oxyhemoglobin (HbO2) around 800 nm. In order to test the technique, we combined three superluminescent light emitting diodes (SLED) together in a Fourier Domain Common Path OCT (FD-CP-OCT) set-up. The result using chicken embryo in vivo shows that we are able to obtain highly localized oxygen saturation variation.

Paper Details

Date Published: 25 November 2009
PDF: 6 pages
Proc. SPIE 7634, Optical Sensors and Biophotonics, 76340W (25 November 2009); doi: 10.1117/12.851806
Show Author Affiliations
Xuan Liu, Johns Hopkins Univ. (United States)
Jin U Kang, Johns Hopkins Univ. (United States)


Published in SPIE Proceedings Vol. 7634:
Optical Sensors and Biophotonics
Xingde Li; Qingming Luo; Vasilis Ntziachristos; Yoshiaki Yasuno, Editor(s)

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