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Proceedings Paper

Xerogel-based molecularly imprinted polymers for explosives detection
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Paper Abstract

Molecularly imprinted polymers (MIPs) can be utilized as artificial recognition elements for target chemical analytes of interest. Molecular imprinting involves arranging polymerizable functional monomers around a template followed by polymerization and template removal. The selectivity for the target analyte is based on the spatial orientation of the binding site and covalent or noncovalent interactions between the functional monomer and the analyte. The polymer materials of particular interest are sol-gel-derived xerogels. To allow for increased target recognition, the xerogel has specific functional groups, which allow for polymer interactions with the template molecule (and target analyte). In a sensor format, the recognition event is monitored with some form of transduction. MIP technology is still in its infancy and limitations such as non-specific binding may be overcome utilizing surface enhanced Raman scattering (SERS) as an integrated transduction method for enhanced sensor performance. The objective of the present work is to create a sensitive and selective MIP-SERS sensing platform for 2,4,6-trinitrotoluene (TNT).

Paper Details

Date Published: 5 May 2010
PDF: 9 pages
Proc. SPIE 7665, Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XI, 76650W (5 May 2010); doi: 10.1117/12.850129
Show Author Affiliations
Ellen L. Holthoff, U.S. Army Research Lab. (United States)
Dimitra N. Stratis-Cullum, U.S. Army Research Lab. (United States)
Mikella E. Hankus, U.S. Army Research Lab. (United States)


Published in SPIE Proceedings Vol. 7665:
Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XI
Augustus Way Fountain; Patrick J. Gardner, Editor(s)

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