Share Email Print
cover

Proceedings Paper

A porous silicon based microarray for label-free optical detection of DNA hybridization
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

In this work, we have fabricated a porous silicon (PSi) Bragg reflectors microarray using a proper technological process based on photolithography and electrochemical anodization of silicon. Each element of the array is characterized by a diameter of 200 μm. The PSi structures have been used as platform to immobilize label-free DNA probe and a simple optical method has been employed to investigate the interaction between probe-DNA and its complementary target. In order to confirm the specificity of the DNA hybridization, we have also verified that the reaction of probe-DNA with non-complementary DNA did not occur.

Paper Details

Date Published: 17 February 2010
PDF: 5 pages
Proc. SPIE 7606, Silicon Photonics V, 76060E (17 February 2010); doi: 10.1117/12.848471
Show Author Affiliations
Ilaria Rea, Institute for Microelectronics and Microsystems, National Council of Research (Italy)
Giuseppe Coppola, Institute for Microelectronics and Microsystems, National Council of Research (Italy)
Mariano Gioffrè, Institute for Microelectronics and Microsystems, National Council of Research (Italy)
Edoardo De Tommasi, Institute for Microelectronics and Microsystems, National Council of Research (Italy)
Ivo Rendina, Institute for Microelectronics and Microsystems, National Council of Research (Italy)
Annalisa Lamberti, Univ. of Naples Federico II (Italy)
Luca De Stefano, Institute for Microelectronics and Microsystems, National Council of Research (Italy)


Published in SPIE Proceedings Vol. 7606:
Silicon Photonics V
Joel A. Kubby; Graham T. Reed, Editor(s)

© SPIE. Terms of Use
Back to Top