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Proceedings Paper

Microcavities in photonic crystal waveguides for biosensor applications
Author(s): Sudeshna Pal; Elisa Guillermain; Rashmi Sriram; Benjamin Miller; Philippe M. Fauchet
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Paper Abstract

In this study, resonant microcavities in photonic crystal (PhC) waveguides are investigated for biosensing applications. The device architecture consists of a PhC waveguide with a defect line for guiding the transmission of light. Resonant microcavities created by changing the radius of a hole adjacent to the defect line are coupled to the PhC waveguide. Detection is based on shifts in the resonance wavelength observed in the transmission spectra. The PhC waveguide device is fabricated on silicon-on-insulator (SOI) wafers using electron beam lithography and reactive-ion etching (RIE). Receptor molecules are attached to the defects in the device by standard amino-silane and glutaraldehyde crosslinking chemistry. Preliminary results demonstrate successful detection of human IgG molecules as the target at large concentration levels of 500 μg/ml. Such PhC waveguide devices are advantageous for medical diagnostics and biosecurity applications as they allow rapid, label-free, and sensitive detection of multiple analytes in a single platform.

Paper Details

Date Published: 17 February 2010
PDF: 10 pages
Proc. SPIE 7553, Frontiers in Pathogen Detection: From Nanosensors to Systems, 755304 (17 February 2010); doi: 10.1117/12.848237
Show Author Affiliations
Sudeshna Pal, Univ. of Rochester (United States)
Elisa Guillermain, Univ. of Rochester (United States)
Rashmi Sriram, Univ. of Rochester (United States)
Benjamin Miller, Univ. of Rochester (United States)
Philippe M. Fauchet, Univ. of Rochester (United States)


Published in SPIE Proceedings Vol. 7553:
Frontiers in Pathogen Detection: From Nanosensors to Systems
Philippe M. Fauchet; Benjamin L. Miller, Editor(s)

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